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Removal of pyrazinamide and its by-products from water: Treatment by electro-Fenton process and feasibility of a biological post-treatment

Mohamed Reda Arhoutane, Muna Sh. Yahya, Miloud El Karbane, Aicha Guessous, Hind Chakchak, Kacem El Kacemi


This paper reports a study on oxidative degradation and mineralization of pyrazinamide in an aqueous medium at pH = 3 and room temperature (≈ 19 °C) by the electro-Fenton process, using carbon felt as a cathode and platinum as an anode. The degradation/mineralization is assessed by the chemical oxygen demand by analyzing applied current intensity and concentration of Fe2+ catalyst. Thus, the main objective is to determine the optimal values of these parameters. Some stable intermediate products have been identified using high-performance liquid chromatography and liquid chromatography tandem mass spectrometry, which show the successive formation of the aromatic/cyclic organics and aliphatic intermediates. The second part of this work corresponds to the study of the biodegradability giving by the ratio: BOD5/COD during the mineralization of pyrazinamide by EF in order to examine the possibility of combining electro-Fenton with a biological post-treatment. 

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